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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANXA4
All Species:
19.7
Human Site:
Y249
Identified Species:
54.17
UniProt:
P09525
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09525
NP_001144.1
319
35883
Y249
C
M
R
N
K
S
A
Y
F
A
E
K
L
Y
K
Chimpanzee
Pan troglodytes
A5A6L7
327
36886
Y257
C
T
Q
N
L
H
S
Y
F
A
E
R
L
Y
Y
Rhesus Macaque
Macaca mulatta
XP_001097807
321
36004
Y251
C
M
R
N
K
S
A
Y
F
A
E
K
L
Y
K
Dog
Lupus familis
XP_536401
510
55030
F440
C
L
K
N
T
P
A
F
F
A
E
R
L
N
K
Cat
Felis silvestris
Mouse
Mus musculus
P97429
319
35971
Y249
C
M
R
S
K
P
S
Y
F
A
E
R
L
Y
K
Rat
Rattus norvegicus
P55260
319
35830
Y249
C
M
R
N
K
P
A
Y
F
A
E
R
L
Y
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P17153
321
36180
Y250
C
I
R
S
V
P
A
Y
F
A
E
T
L
Y
Y
Frog
Xenopus laevis
Q92125
512
53295
F444
C
A
I
N
R
P
L
F
F
R
D
R
L
C
R
Zebra Danio
Brachydanio rerio
NP_861429
321
35616
F251
C
I
K
N
K
P
A
F
F
A
E
R
L
Y
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.1
98.4
36.4
N.A.
91.5
92.4
N.A.
N.A.
57.9
31.6
63.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
71.5
99.3
48.6
N.A.
96.8
96.8
N.A.
N.A.
72.9
42.7
79.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
53.3
100
53.3
N.A.
73.3
86.6
N.A.
N.A.
60
26.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
73.3
100
80
N.A.
93.3
93.3
N.A.
N.A.
73.3
60
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
0
0
67
0
0
89
0
0
0
0
0
% A
% Cys:
100
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
89
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
34
100
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
23
12
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
23
0
56
0
0
0
0
0
0
23
0
0
67
% K
% Leu:
0
12
0
0
12
0
12
0
0
0
0
0
100
0
0
% L
% Met:
0
45
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
78
0
0
0
0
0
0
0
0
0
12
0
% N
% Pro:
0
0
0
0
0
67
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
56
0
12
0
0
0
0
12
0
67
0
0
12
% R
% Ser:
0
0
0
23
0
23
23
0
0
0
0
0
0
0
0
% S
% Thr:
0
12
0
0
12
0
0
0
0
0
0
12
0
0
0
% T
% Val:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
0
0
0
0
0
78
23
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _